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Adalat® Research

Adalat® (nifedipine GITS) is one of the most well-researched antihypertensive agents. Recent trials have focused on its effects beyond blood-pressure reduction:
INSIGHT was the first double-blind, prospective, randomised study to investigate the clinical outcome of treatment with Adalat® once-daily vs conventional treatment in hypertensive patients with additional cardiovascular risk factors.

In addition to the main trial, INSIGHT side-arm studies and several additional INSIGHT subanalyses were performed, each of which have added to our understanding of the progression of cardiovascular disease in hypertensive patients.

In ENCORE, the primary objectives were to assess the effects of treatment with Adalat® and/or cerivastatin on coronary endothelial dysfunction, coronary morphology and the progression of coronary atherosclerosis.

The ACTION trial provides information on how blood-pressure control and additional effects of Adalat® translate into long-term clinical benefits. For further information on the results, please have a look at our ACTION website.

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